Council Officer – Website Group
Affiliation
Laboratory of Angiogenesis and Inflammation
Department of Biomedicine at Aarhus University
Biosketch
Associate Professor Joanna Maria Kalucka holds dual appointments at the Steno Diabetes Center Aarhus (SDCA) and the Department of Biomedicine at Aarhus University, where she leads a dynamic international research team. Her group focuses on uncovering the metabolic signatures of dysfunctional endothelial cells in inflammatory pathological conditions, such as cancer and obesity.
Before joining Aarhus University, Joanna was awarded a postdoctoral fellowship by the Research Foundation Flanders to study endothelial cell metabolism at KU Leuven in Belgium. During this time, she identified key metabolic adaptations in quiescent endothelium (Kalucka et al., Cell Metabolism, 2018) and produced the first murine endothelial cell atlas using single-cell sequencing (Kalucka et al., Cell, 2020), which has since become a critical resource for the scientific community.
Joanna’s unique background in engineering and biomedical sciences enables her to lead innovative projects that incorporate cutting-edge, cross-disciplinary technologies. Her team has established infrastructure for single-cell, nuclei, and RNA sequencing and uses advanced imaging technologies to validate their findings and gain mechanistic insights. To ensure the translational impact of her work, Joanna collaborates closely with clinicians at Aarhus University Hospital and other international medical centers.
Mission Statement
At the Laboratory of Angiogenesis and Inflammation, our mission is to deepen our understanding of the vascular system and its critical role in health and disease. Our research centers on the biology of endothelial cells, investigating their responses to inflammation and pro-inflammatory stimuli and how these factors shape endothelial metabolism. By unraveling these processes, we aim to uncover the mechanisms that govern blood vessel function and their alterations in conditions such as cancer, obesity, and systemic inflammation.
To achieve this, we leverage a wide range of advanced techniques, including multi-omics technologies, cell-based models, organoid cultures, and cutting-edge imaging methods. These tools enable us to link molecular changes to the structure and function of blood vessels and vascular networks. Our research emphasizes the integration of diverse approaches to provide a holistic understanding of vascular biology.
Through this work, we strive to make meaningful contributions to vascular research and to enhance our understanding of diseases affecting the vascular system. We are committed to fostering collaboration and innovation, working across disciplines to generate insights that address critical challenges in human health.
Publications
https://pubmed.ncbi.nlm.nih.gov/?term=Kalucka+J&sort=date
https://pure.au.dk/portal/en/persons/joanna.kalucka%40biomed.au.dk
Internet
Web: https://biomed.au.dk/kalucka-lab
X/twitter @JoannaKalucka
