Treasurer – Seminar Series Group
Cardiovascular research institute (CARIM), Maastricht University Medical Center, Maastricht, Netherlands
Centre for Cardiovascular Science (CVS), University of Edinburgh, Edinburgh, UK.
Dr Judith Sluimer (Rotterdam, The Netherlands) defended her PhD thesis at Maastricht University in 2008. She established the first proof of hypoxia in human and murine atherosclerosis and investigated the hypoxia-dependent formation and leaky phenotype of atherosclerotic plaque angiogenesis. After her PhD defence, she joined the lab of Prof. Ira Tabas (Columbia University, NYC, USA) in 2008 as a post-doctoral fellow to further her expertise in macrophage apoptosis, efferocytosis and autophagy. Since 2010, Judith has established an independent research line to investigate molecular mechanisms in cardiovascular pathophysiology in the Department of Pathology of Maastricht UMC+ with a CARIM tenure track. In addition to research and teaching, she has been mentor of BSc students in Medicine and Biomedical Sciences since 2011. She is full professor of cardiovascular pathophysiology since 2020. Judith Sluimer serves as EVBO council member since 2017, and as treasurer since 2019. In 2019 she was local the organizer of ESM-EVBO conference in Maastricht.
Judith Sluimer’s research interests lie in understanding the molecular mechanisms in cardiovascular pathophysiology, specifically the pathogenesis of atherosclerosis and vascular ageing. She investigates the molecular mechanisms underlying the responses of macrophages and mesenchymal cells in vascular physiology and pathology to cellular stress (hypoxia, autophagy, lipids), and resulting changes in cellular heterogeneity or identity, and intercellular communication. She combines experimental in vivo and in vitro models with single cell sequencing, studies involving human subjects and tissue samples, and non-invasive imaging of vulnerable plaques.