EVBO Publication Highlight Feb 2020

Single-cell transcriptome analyses reveal novel targets modulating cardiac neovascularization by resident endothelial cells following myocardial infarction

Ziwen Li,  Emmanouil G Solomonidis,  Marco Meloni,  Richard S Taylor,  Rodger Duffin, Ross Dobie,  Marlene S Magalhaes,  Beth E P Henderson,  Pieter A Louwe,  Gabriela D’Amico, Kairbaan M Hodivala-Dilke,  Ajay M Shah,  Nicholas L Mills,  Benjamin D Simons, Gillian A Gray,  Neil C Henderson,  Andrew H Baker,  Mairi Brittan. European Heart Journal, Volume 40, Issue 30, 7 August 2019, Pages 2507–2520. DOI: https://doi.org/10.1093/eurheartj/ehz305

Microsoft PowerPoint - Brittan_graphical abstract_Feb2020_mod

Other selected publications

Marín-Juez R … Stainier DYR. Coronary Revascularization During Heart Regeneration Is Regulated by Epicardial and Endocardial Cues and Forms a Scaffold for Cardiomyocyte Repopulation. Dev Cell. 2019 Nov 18. DOI: 10.1016/j.devcel.2019.10.019.

Geudens I*, Coxam B* … Gerhardt H.  Artery-vein specification in the zebrafish trunk is pre-patterned by heterogeneous Notch activity and balanced by flow-mediated fine tuning. Development. 2019 Aug 27. DOI: 10.1242/dev.181024.

Kniebs C … Thiebes AL. Influence of Different Cell Types and Sources on Pre-Vascularisation in Fibrin and Agarose–Collagen Gels. Organogenesis 2019 Dec 6, DOI: 10.1080/15476278.2019.1697597.

Mentrup T … Schröder B. Atherogenic LOX-1 signaling is controlled by SPPL2-mediated intramembrane proteolysis. J Exp Med. 2019 Apr 1. DOI: 10.1084/jem.20171438.

Lowe V … Pellet-Many C.  Neuropilin 1 mediates epicardial activation and revascularization in the generating zebrafish heart. Development. 2019 Jul 2. DOI: 10.1242/dev.174482

Pedrosa AR … Hodivala-Dilke KM. Tumor angiogenesis is differentially regulated by phosphorylation of endothelial cell focal adhesion kinase tyrosines-397 and -861. Cancer Res. 2019 Sep 1. DOI: 10.1158/0008-5472.CAN-18-3934

Jafree DJ…Long DA. Spatiotemporal dynamics and heterogeneity of renal lymphatics in mammalian development and cystic kidney disease. Elife. 2019 Dec 6. DOI: 10.7554/eLife.48183

EVBO Publication Highlight – how to submit your publication

To highlight the most interesting and impactful papers published by EVBO members recently, please send the following information to Dr. Beata Wojciak-Stothard (b.wojciak-stothard@imperial.ac.uk):

  1. Author list, title, Journal and Digital Object Identifier (DOI)
  2. 3-5 bullet points (max. 150 characters with spaces/bullet point)  highlighting the novelty and impact of this study in the field of vascular biology.

The EVBO Awards Committee will make a final selection and ask the sender to provide a summary figure to be added to the EVBO web page/newsletter and a  link to website/social media.