Professor of Physiology
Institute for Vascular Signalling
Centre for molecular medicine
Theodor Stern Kai 7
60596 frankfurt am Main
Ingrid Fleming is a Professor of Physiology and heads the Institute for vascular Signalling at the Goethe University in Frankfurt, Germany. Although the name sounds German Ingrid is originally from Northern Ireland and studied in Birmingham (BSc), as well as in Strasbourg (PhD) before moving to Freiburg for a postdoctoral position. The original plan to stay for two years fell quickly by the wayside and she has been working in Frankfurt since 1993. Following on from PhD work concentrating on the inducible nitric oxide synthase, Ingrid has concentrated on the vascular endothelium and particularly on signal
transduction. Current interests centre on keeping the endothelium functional and particular projects include the
regulation of the endothelial nitric oxide synthase, cytochrome P450 epoxygenases/endothelium derived hyperpolarising factor, signal transduction by the angiotensin-converting enzyme and proteases in platelets. Ingrid Fleming also serves on the editorial board of several prominent journals and was one of the co-organisers of the 3rd European Meeting on Vascular Biology and Medicine.
I was bitten in the vascular biology bug relatively early on but I was lucky enough to be involved in the identification of the inducible nitric oxide synthase in vascular smooth muscle cells right from the very beginning. While my current interests were centred on signal transduction, a lot of which is performed in cell culture, I place a lot of emphasis on
“translational science” i.e., performing parallel studies in vivo and where possible in humans. This means developing close contacts and active collaborations with clinical scientists. I believe that the EVBO has the potential to become an essential European network for basic scientists and clinical colleagues interested in vascular biology and that collaboration is necessary to make the most of the scientific potential that exists in Europe.