Postdoctoral researcher in vascular biology; Karolinska Institutet, Dept of Medical Biochemistry and Biophysics, Stockholm, Sweden
The lab and technologies
The Jakobsson lab investigates processes of blood vessel morphogenesis and function in development and disease, with the aim to develop new therapies. The lab utilizes mouse models of human disease based on inducible genetic loss- and gain- of-function in combination with state-of-the-art confocal live imaging (multi-photon, in vivo and ex vivo). In addition the environment provides access to drug screening platforms, proteomics and single cell RNA sequencing. The lab has an extensive international scientific network and is integrated in a highly interactive scientific environment with close contact with the clinic. Recent publications from the lab: Jin et al, Nat. Cell Biol., 2017; Wang et al, Development, 2017; Wang et al, Sci. Rep., 2018.
The lab aims to find novel ways of modulating angiogenesis and vessel function. The studies build on the lab’s previous findings on endothelial cell- signalling, behaviour and gene expression in vascular patterning and malformation in the CNS. The project will focus on mechanisms of establishment of arteries and veins and maintenance of vessel function in relation to human disease. Data acquisition is facilitated by novel mouse models in combination with abovementioned technologies, including single cell RNA seq. Please visit the lab website (http://ki.se/en/mbb/lars-jakobsson-group) for an overview.
The Department and location
The Department of Medical Biochemistry and Biophysics with its 450 employees conducts biomedical research and education at the absolute forefront. The postdoc will work in Dr. Lars Jakobsson’s group at the Division of Vascular Biology, in a vibrant new research center, Biomedicum, in central Stockholm. Please see Biomedicum Stockholm
To qualify, the applicant must hold (or shortly obtain) a doctor’s degree, acquired no later than two years prior application deadline, in the fields of molecular/ developmental biology, biotechnology/engineering or similar. Please see the full advertisement for further details requirement.
Type of position
The postdoc position is available immediately. Funding, in the form of a scholarship is tax-exempt and ranges between 25 000 to 28 000 SEK/month. This funding is provided for a maximum of two years, with a possibility for extension of another two years on complete salary scheme.
Apply before Feb 17. Please follow the link for further instructions and application.
Please contact Lars.email@example.com for further information.