{"id":3302,"date":"2026-04-10T11:30:13","date_gmt":"2026-04-10T11:30:13","guid":{"rendered":"https:\/\/evbo.org\/?post_type=job_listing&p=3302"},"modified":"2026-04-10T11:53:35","modified_gmt":"2026-04-10T11:53:35","slug":"imperial-college-london-london-27-research-associate-in-lymphatic-biology","status":"publish","type":"job_listing","link":"https:\/\/evbo.org\/index.php\/job\/imperial-college-london-london-27-research-associate-in-lymphatic-biology\/","title":{"rendered":"Research Associate in Lymphatic Biology"},"content":{"rendered":"

About the role:<\/strong><\/p>\n

As a MRC-funded Postdoctoral Research Associate you will spearhead an innovative investigation into the transcription factor ERG to determine its role as a master regulator of lymphatic identity and immune response. Working at a world-leading institution within a high-impact collaborative environment, you will employ\u00a0in vivo\u00a0models with state-of-the-art molecular and cellular assays to uncover how ERG functions as an “immune gatekeeper” during both steady-state and inflammatory challenges. Ultimately, your findings will define a new roadmap for therapeutic targets to treat debilitating conditions like primary lymphoedema, directly bridging the gap between fundamental molecular science and patient benefit.<\/p>\n

What you would be doing:<\/strong><\/p>\n

In this role, you will lead investigations into how the transcription factor ERG regulates lymphatic identity and immune cell trafficking. Your responsibilities will include performing\u00a0in vivo\u00a0functional assays to quantify lymphatic drainage and immune cell trafficking. You will utilize single-cell transcriptomics and high-resolution multiplexed imaging to map cellular landscapes in mouse and human tissues. Additionally, you will conduct mechanistic studies to identify the role of ERG in lymph node maintenance. Throughout, you will develop advanced analytical skills and benefit from a dynamic and collaborative research environment.<\/p>\n

What we are looking for:<\/strong><\/p>\n

We are looking for an ambitious and highly motivated postdoctoral researcher with a PhD in vascular biology, immunology, or cell biology to join this collaborative project. While a full person specification is available in the job description, we are specifically looking for candidates who can demonstrate:<\/p>\n

In Vivo Expertise<\/em>:\u00a0Advanced techniques using genetically modified mice, including functional lymphatic assays and immune trafficking models.<\/p>\n

High-Resolution Imaging<\/em>:\u00a0Proficiency in spatially-resolved multiplexed imaging and confocal whole-mount tissue analysis.<\/p>\n

scRNA-seq<\/em>:\u00a0Experience designing 10x Genomics experiments and performing computational data analysis.<\/p>\n

Molecular Biology<\/em>:\u00a0Skills in CRISPR\/siRNA inhibition and\u00a0in vitro\u00a0functional assays.<\/p>\n

Data Analysis:<\/em>\u00a0Ability to interpret high-dimensional datasets to identify gene signatures and cellular interactions.<\/p>\n

Collaborative Mindset<\/em>:\u00a0Proactive approach to sharing expertise and publishing high-quality manuscripts.<\/p>\n

Ambition<\/em>:\u00a0Driven to acquire new skills and develop an independent academic research career.<\/p>\n

What we can offer you:<\/strong><\/p>\n

By joining this project, you will launch your career as an independent investigator through several key benefits:<\/p>\n

High-Impact Collaboration<\/em>:\u00a0Work across a unique partnership between Imperial College London and the University of Nottingham, gaining expertise in ERG transcriptional regulation and immune response.
\nCutting-Edge Technology<\/em>:\u00a0Gain mastery of state-of-the-art platforms, including 10x Genomics for single-cell transcriptomics and spatially-resolved multiplexed imaging.
\nTranslational Impact<\/em>:\u00a0Contribute to clinically relevant research alongside City St. George\u2019s to identify therapeutic targets for conditions like primary lymphoedema.
\nScientific Recognition<\/em>:\u00a0Lead the dissemination of findings through high-quality manuscripts and international conference presentations.
\nLeading Benefits<\/em>:\u00a0Receive a sector-leading salary and 41 days of annual leave.
\nCareer Structure<\/em>:\u00a0This 36-month post provides dedicated support to develop independent research ideas for future senior academic roles.<\/p>\n

Further Information:<\/strong><\/p>\n

This is a Full time fixed-term (3 years) role based at our White City Campus (Hammersmith Hospital site).<\/p>\n

If you require any further details on the role please contact: Dr Graeme Birdsey (g.birdsey@imperial.ac.uk). Lab webpage:\u00a0https:\/\/profiles.imperial.ac.uk\/g.birdsey<\/p>\n","protected":false},"author":117,"featured_media":0,"template":"","meta":{"give_campaign_id":0,"om_disable_all_campaigns":false,"pmpro_default_level":"","_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"_uf_show_specific_survey":0,"_uf_disable_surveys":false,"_price":"","_stock":"","_tribe_ticket_header":"","_tribe_default_ticket_provider":"","_tribe_ticket_capacity":"","_ticket_start_date":"","_ticket_end_date":"","_tribe_ticket_show_description":"","_tribe_ticket_show_not_going":false,"_tribe_ticket_use_global_stock":"","_tribe_ticket_global_stock_level":"","_global_stock_mode":"","_global_stock_cap":"","_tribe_rsvp_for_event":"","_tribe_ticket_going_count":"","_tribe_ticket_not_going_count":"","_tribe_tickets_list":"[]","_tribe_ticket_has_attendee_info_fields":false,"_promoted":"","_job_location":"London","_application":"https:\/\/www.jobs.ac.uk\/job\/DRB931\/research-associate-in-lymphatic-biology","_company_name":"Imperial College London","_company_website":"https:\/\/profiles.imperial.ac.uk\/g.birdsey","_company_tagline":"","_company_twitter":"@Birdseylab","_company_video":"","_filled":0,"_featured":0,"_remote_position":0,"_job_salary":"\u00a349,017 to \u00a350,893","_job_salary_currency":"GBP","_job_salary_unit":"YEAR"},"job-types":[27],"class_list":{"0":"post-3302","1":"job_listing","2":"type-job_listing","3":"status-publish","4":"hentry","5":"pmpro-has-access","7":"job-type-post-doctoral"},"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/evbo.org\/index.php\/wp-json\/wp\/v2\/job-listings\/3302","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/evbo.org\/index.php\/wp-json\/wp\/v2\/job-listings"}],"about":[{"href":"https:\/\/evbo.org\/index.php\/wp-json\/wp\/v2\/types\/job_listing"}],"author":[{"embeddable":true,"href":"https:\/\/evbo.org\/index.php\/wp-json\/wp\/v2\/users\/117"}],"wp:attachment":[{"href":"https:\/\/evbo.org\/index.php\/wp-json\/wp\/v2\/media?parent=3302"}],"wp:term":[{"taxonomy":"job_listing_type","embeddable":true,"href":"https:\/\/evbo.org\/index.php\/wp-json\/wp\/v2\/job-types?post=3302"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}