Lecturer in Vascular Sciences
National Heart and Lung Institute, Imperial College London,
Hammersmith Hospital Du Cane Road
London W12 0NN
1998 PhD in Molecular Cell Biology, MRC Lab for Mol. Cell Biol. & Dept. of Biology, University College London
1994 BSc (Hons) Applied Biochemistry (2.1), Liverpool John Moores University, Liverpool.
Memberships and Committees
• National Lung & Heart Institute, Higher Degrees Research Committee (2013 – present)
• Medical Education Ethics Committee (MEEC), Faculty of Medicine, Imperial College London (2015- present)
• Organising Committee of the London Vascular Biology Forum (2013 – present)
• European Vascular Biology Organisation (EVBO); North American Vascular Biology Organisation (NAVBO); British Society for Cardiovascular Research; British Society for Cell Biology; Biochemical Society.
Selected Recent Publications
1. Shah AV, Birdsey GM, Peghaire CM, Pitulescu ME, Dufton NP, Yang Y, Weinberg I, Osuna Almagro L, Payne L, Mason JC, Gerhardt H, Adams RH, Randi AM. (2017) The endothelial transcription factor ERG mediates Angiopoietin-1-dependent control of Notch signalling and vascular stability. Nature Communications. In press.
2. Bauer A, Mylroie H, Thornton C, Calay D, Birdsey GM, Kiprianos AP, Wilson GK, Soares MP, Yin X, Mayr M, Randi AM, Mason JC. (2016) Identification of cyclins A1, E1 and vimentin as downstream targets of heme oxygenase- 1 in vascular endothelial growth factor-mediated angiogenesis. Scientific Reports 6: 29417
3. Shah AV, Birdsey GM, Randi AM. (2016) Regulation of endothelial homeostasis, vascular development and angiogenesis by the transcription factor ERG. Vascular Pharmacology 86:3-13
4. Birdsey GM, Shah AV, Reynolds LE, Dufton N, Almagro LO, Yang Y, Aspalter IM, Khan ST, Mason JC, Dejana E, Gottgens B, Hodivala-Dilke KM, Gerhardt H, Adams RH, Randi AM. (2015) The endothelial transcription factor ERG promotes vascular stability and growth through Wnt/β-catenin signaling. Developmental Cell 32(1): 82–96
5. Dowsett L, Piper S, Slaviero A, Dufton N, Wang Z, Boruc O, Delahaye M, Colman L, Kalk E, Tomlinson J, Birdsey G, Randi AM, Leiper J. (2015) Endothelial Dimethylarginine Dimethylaminohydrolase 1 is an important regulator of angiogenesis but does not regulate vascular reactivity or hemodynamic homeostasis. Circulation 131(25):2217-25
6. Shapiro SE, Nowak AA, Wooding C, Birdsey G, Laffan MA, McKinnon TA. (2014) The von Willebrand factor predicted unpaired cysteines are essential for secretion. J Thromb Haemost. 12(2):246-54
7. Kostourou V, Lechertier T, Reynolds LE, Lees DM, Baker M, Jones DT, Tavora B, Ramjaun AR, Birdsey GM, Robinson SD, Parsons M, Randi AM, Hart IR, Hodivala-Dilke K (2013) FAK-heterozygous mice display enhanced tumour angiogenesis. Nature Communications 4:2020.
I have actively worked in the field of cardiovascular research for over 15 years, with a track record of publishing in high impact journals, including Blood, Developmental Cell, Nature Communications, and Circulation. I also have experience in the delivery of vascular science courses to undergraduate and postgraduate students. As a member of the organising committee of the London Vascular Biology Forum, I have played a key role in helping to arrange quarterly symposia and networking sessions bringing together PhD students and postdoc trainees with leading vascular scientists from the London universities.
Throughout my training and now as a junior faculty member at Imperial College London, I have been committed to promoting the dissemination of scientific research to the widest possible audience, especially through encouraging younger scientists to participate in conferences and discussion forums. If elected to the EVBO Council, I will be a strong advocate in promoting the aims of the EVBO as the premier European forum for researchers in the field of vascular biology. I believe that my role in the London Vascular Biology Forum and wider experiences in cardiovascular research and teaching will enable me to be an active contributor to the running of the EVBO. Drawing on my experiences in enhancing the profile of the LVBF, I will encourage the EVBO to embrace social media platforms such as Twitter and Facebook in order expand the EVBO membership, especially amongst students and junior postdocs.
I look forward to helping to contribute to the continuing success of the EVBO over the coming years.